10) Elecrophilic aromatic substitution:

PHARMACEUTICAL ORGANIC CHEMISTRY

CHAPTER-10

Elecrophilic aromatic substitution

This chapter comes under Organic Chemistry. It deals with the following;

Elecrophilic aromatic substitution: Effect of substituent groups, determination of orientation, determination of relative reactivity, classification of substituent group, mechanism of nitration, sulphonation, halogenation, friedel craft alkylation, friedel craft acylation, reactivity and orientation, activating and deactivating O,P,M directing groups, electron release via resonance, effect of halogen on electrophilic aromatic substitution in alkyl benzene, side chain halogination of alkyl benzene, resonance stabilization of benzyl radical.

Text books 

a. T.R.Morrison and R. Boyd - Organic chemistry, 

b. Bentley and Driver-Text book of Pharmaceutical chemistry 

c. I.L.Finer- Organic chemistry, the fundamentals of chemistry 

Reference books 

a. Organic chemistry – J.M.Cram and D.J.Cram 

b. Organic chemistry- Brown 

c. Advanced organic chemistry- Jerry March, Wiley 

d. Organic chemistry- Cram and Hammered, Pine Hendrickson 

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