Glance on MOYAMOYA DISEASE

MOYAMOYA DISEASE

By SNEHA MAVIS

Moyamoya disease is a rare, progressive cerebrovascular disorder characterized by blocked arteries in the basal ganglia. Moyamoya, a Japanese term meaning "puff of smoke," refers to the tangled appearance of tiny vessels that compensate for blockage.Though its precise cause is unknown, a mix of environmental and genetic variables are believed to be responsible for Moyamoya disease.

Symptoms:

• Headache.
• Seizures.
• Weakness, numbness or paralysis on one side of the body.
• Vision problems.
• Trouble speaking or understanding.
• Cognitive or developmental delays.
• Involuntary movements. 

Diagnosis:

• Magnetic resonance imaging (MRI).
• Computerized tomography (CT) scan.
• Cerebral angiogram.
• Positron emission tomography (PET) scan
• Electroencephalogram (EEG)
• Transcranial Doppler ultrasound.

Medical management

• Aspirin
• Anticoagulants
• Anticonvulsants
• Calcium channel blockers

Surgical management 

• Direct revascularization procedures
• Indirect Bypass Surgery (EDAS or EMS)
• Encephaloduroarteriosynangiosis (EDAS)
• Revascularization Surgery