Unit 2- Conversion from intravenous to oral dosing

CLINICAL PHARMACOKINETICS & PHARMACOTHERAPEUTIC DRUG MONITORING

UNIT-2

Design of dosage regimens

Conversion from intravenous to oral dosing

 

Get the notes below!

Conversion from intravenous to oral dosing

 The ideal route is one that achieves serum concentrations sufficient to produce the desired effect without producing undesired effects.  Patients must switch to oral (PO) therapy to continue treatment after a course of intravenous (IV) therapy.  Oral formulations: easier to administer, safe, and achieve desired therapeutic concentrations.  Patients are more comfortable if they do not have an IV catheter in place  Attachment to an IV pole can restrict movement, which can hinder early and/or frequent ambulation.  Parenteral therapy: are at an increased risk for infusion related adverse event

Thanks to JOHN FELIX.