PHARMACOLOGY TEXTBOOK - K D TRIPATHI
Pharmacology is both a basic and an applied science. It forms the backbone of rational thera-
peutics. Whereas the medical student and the prescribing physician are primarily concerned
with the applied aspects, correct and skilful application of drugs is impossible without a proper
understanding of their basic pharmacology. Medical pharmacology, therefore, must include both
fundamental background and clinical pharmacological information. Objective and quantitative
data on the use of drugs in man, i.e., relationship between plasma concentration and intensity
of therapeutic/toxic actions, plasma half lives, relative efficacy of different medications and
incidence of adverse effects etc., are being obtained with the aim of optimising drug therapy.
The concepts regarding mechanism of action of drugs are changing. In addition, new drugs
are being introduced in different countries at an explosive pace. A plethora of information
thus appears to be important. However, trying to impart all this to a medical student would
be counter-productive.
One of the important aims of this book is to delineate the essential information about drugs.
The opening sentence in each chapter defines the class of drugs considered. A ‘prototype’ ap-
proach has been followed by describing the representative drug of a class followed by features
by which individual members differ from it. Leading trade names have been included. Clinically
relevant drug interactions have been mentioned. Clear-cut guidelines on selection of drugs and
their clinical status have been outlined on the basis of current information. Original, simple
and self-explanatory illustrations, tables and flowcharts have been used with impunity. Selected
chemical structures are depicted. Recent developments have been incorporated. However, discre-
tion has been used in including only few of the multitude of new drugs not yet available in
India. This is based on their likelihood of being marketed soon. The information and views
have been arranged in an orderly sequence of distinct statements.
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